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Longitudinal Study: LSAC
Title: Brief Report: Pregnancy, Birth and Infant Feeding Practices: A Survey-Based Investigation into Risk Factors for Autism Spectrum Disorder
Authors: Whitely, Aleesha
Shandley, Kerrie
Huynh, Minh
Brown, Christine M
Austin, David W
Bhowmik, Jahar
Publication Date: Nov-2022
Pages: 5072–5078
Keywords: Analgesia
Autism spectrum disorder
Labour interventions
Pregnancy complications
Risk factors
Abstract: A succession of interconnected environmental factors is believed to contribute substantially to the development of autism spectrum disorder (ASD). This exploratory study therefore aims to identify potential risk factors for ASD that are associated with pregnancy, birth and infant feeding. Demographic and health-related data on children aged 3-13 years (N = 4306) was collected through an online survey completed by biological mothers. A fitted logistic regression model identified advanced maternal age, prenatal bleeding, pre-eclampsia, perinatal pethidine usage, foetal distress before birth and male sex of child as associated with an increased risk of ASD, whereas longer gestational duration demonstrated a protective effect. These findings highlight potential risk factors and predictor interrelationships which may contribute to overall ASD risk.
DOI: 10.1007/s10803-021-05348-3
Keywords: Analgesia; Autism spectrum disorder; Breastfeeding; Labour interventions; Pregnancy complications; Risk factors
Research collection: Journal Articles
Appears in Collections:Journal Articles

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