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https://hdl.handle.net/10620/4499
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DC Field | Value | Language |
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dc.contributor.author | Sung, V | en |
dc.contributor.author | Liu, R | en |
dc.contributor.author | Wake, M | en |
dc.contributor.author | Olds, T | en |
dc.contributor.author | Zubrick, S | en |
dc.contributor.author | Wang, J | en |
dc.contributor.author | Grobler, A | en |
dc.contributor.author | Carew, P | en |
dc.contributor.author | Lycett, K | en |
dc.date.accessioned | 2019-06-14T23:53:26Z | en |
dc.date.accessioned | 2019-05-23T01:58:31Z | en |
dc.date.available | 2019-06-14T23:53:26Z | en |
dc.date.available | 2019-05-23T01:58:31Z | en |
dc.date.issued | 2018-10 | en |
dc.identifier.uri | https://hdl.handle.net/10620/18395 | en |
dc.identifier.uri | http://hdl.handle.net/10620/4499 | en |
dc.description.abstract | Background Hearing loss is a disabling condition whose prevalence rises with age. Obesity—a risk factor common to many non-communicable diseases—now appears to be implicated. We aimed to determine: (1) cross-sectional associations of body composition measures with hearing in mid-childhood and mid-life and (2) its longitudinal associations with 10-year body mass index (BMI) trajectories. Methods Design & Participants: There were 1481 11–12-year-old children and 1266 mothers in the population-based cross-sectional CheckPoint study nested within the Longitudinal Study of Australian Children (LSAC). Anthropometry (CheckPoint): BMI, fat/fat-free mass indices, waist-to-height ratio; LSAC wave 2–6-biennial measured BMI. Audiometry (CheckPoint): Mean hearing threshold across 1, 2 and 4 kHz; hearing loss (threshold > 15 dB HL, better ear). Analysis: Latent class models identifying BMI trajectories; linear/logistic regression quantifying associations of body composition/trajectories with hearing threshold/loss. Results Measures of adiposity, but not fat-free mass, were cross-sectionally associated with hearing. Fat mass index predicted the hearing threshold and loss in children (β 0.6, 95% confidence interval (CI) 0.3–0.8, P < 0.001;, odds ratio (OR) 1.2, 95% CI 1.0–1.4, P = 0.05) and mothers (β 0.8, 95% CI 0.5–1.2, P < 0.001; OR 1.2, 95% CI 1.1–1.4, P = 0.003). Concurrent obesity (OR 1.5, 95% CI 1.1–2.1, P = 0.02) and waist-to-height ratio (WHtR) ≥ 0.6 (OR 1.6, 95% CI 1.2–2.3, P = 0.01) predicted maternal hearing, with similar but attenuated patterns in children. In longitudinal analyses, mothers’, but not children’s, BMI trajectories predicted hearing (OR for severely obese 3.0, 95% CI 1.4–6.6, P = 0.01). Conclusions Concurrent adiposity and decade-long BMI trajectories showed small, but clear, associations with poor hearing in mid-life women, with emergent patterns by mid-childhood. This suggests that obesity may play a role in the rising global burden of hearing loss. Replication and mechanistic and body compositional studies could elucidate possible causal relationships. | en |
dc.subject | Health | en |
dc.title | How body composition influences hearing status by mid-childhood and mid-life: The Longitudinal Study of Australian Children. | en |
dc.type | Journal Articles | en |
dc.identifier.url | https://www.nature.com/articles/s41366-018-0170-6 | en |
dc.identifier.survey | LSAC | en |
dc.identifier.journal | International Journal of Obesity | en |
dc.identifier.volume | 42 | en |
dc.description.pages | 10 | en |
dc.identifier.issue | 10 | en |
local.identifier.id | 5092 | en |
dc.publisher.city | Parkville | en |
dc.subject.dss | Health and wellbeing | en |
dc.relation.survey | LSAC | en |
dc.old.surveyvalue | LSAC | en |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
item.openairetype | Journal Articles | - |
item.fulltext | No Fulltext | - |
Appears in Collections: | Journal Articles |
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