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Longitudinal Study: LSAC
Title: No increased risk of mothers of children with autism having androgen-related cancers in an Australian population based sample
Authors: May, Tamara
Vollenhoven, Beverly
Williams, Katrina 
Publication Date: Oct-2021
Pages: 101858
Keywords: Autism spectrum disorder
Longitudinal study of Australian children
Abstract: Background Some past studies have suggested a link between autism spectrum disorder (ASD) and testosterone related cancers. This study explored androgen-related cancer in mothers of children with and without parent-reported ASD in a prospective Australian population based sample. Methods Odds of self-reported breast, uterine and cervical cancer in mothers of children with and without parent-reported ASD in the Longitudinal Study of Australian Children. This prospective population based study contains two cohorts of children recruited at birth or 4 years of age. Results Of 324 children with parent-reported ASD and 6,948 without, there were no significantly increased odds for children with ASD and mother breast (AOR 1.20 [95 % CI .50, 2.87]), uterine (AOR .92 [95 % CI .05, 15.78]), cervical (AOR 1.23 [95% CI .46, 3.25]) or all cancers (AOR 1.13 [95% CI .58, 2.21]). Conclusions This study found no evidence to support an increased or decreased androgen related cancer risk in mothers of children with parent-reported ASD.
DOI: 10.1016/j.rasd.2021.101858
Research collection: Journal Articles
Appears in Collections:Journal Articles

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